SphygomoCor® XCEL Pulse Wave Analysis (PWA)

  • Clinically validated / FDA Cleared
  • Reimbursement CPT code 93050
  • Accuracy compared to an intravascular catheter
  • Consistently easy to measure in 3 minutes
  • Peer reviewed publications across therapeutic areas

SphygmoCor XCEL Pulse Wave Analysis (PWA) System

ATCOR’s noninvasive PWA technology measures a suite of digital vascular biomarkers (right) to personalize patient care and enhance clinical trial endpoint monitoring.

 
cbpCentral Blood Pressure

What it Is
Calculated using pulse wave analysis and a traditional brachial cuff, central blood pressure measures pressure at the root of the aorta.

Why it Matters
Central blood pressure reflects key vascular issues such as arterial stiffness, which makes it a more accurate predictor of subclinical cardiovascular disease than traditional brachial blood pressure alone.

 
bbpBrachial Blood Pressure

What it Is
Brachial blood pressure measures the pressure of blood at the brachial artery using a blood pressure cuff.

Why it Matters
High blood pressure is a major risk factor for heart disease and stroke, both of which are leading causes of death in the US.

 
sevrSubendocardial Viability Ratio

What it Is
Subendocardial viability ratio measures the supply of blood that flows to your inner heart muscle in relation to demand.

Why it Matters SEVR offers insight into how well a person’s heart can handle the stress of exercise.

 
medical grade heart rateMedical Grade Heart Measurement

What it Is
A beat-to-beat heart rate measurement on par with standard ECG-based methods.

Why it Matters
A consistently high resting heart rate may be a sign of coronary heart disease and is associated with a greater risk of stroke.

 
cppCentral Pulse Pressure

What it Is
The height of pressure at the heart, central pulse pressure shows the pressure to which key organs like the heart, brain, and kidneys are exposed.

Why it Matters
Central pulse pressure helps identify the risk of end organ damage to key organs like the brain, kidney and heart.

 
cppPulse Wave Velocity

What it Is
Pulse wave velocity measures arterial stiffness.

Why it Matters
Increases in arterial stiffness are generally based on the loss of elasticity in the aorta artery walls over time and increases the strain on the heart from heightened pressures. Increased aortic stiffness using PWV is a validated predictor of cardiovascular events and all-cause mortality.

 
augmentation pressureAugmentation Pressure

What it Is
Augmentation pressure refers to the increase in central aortic pressure caused pressure wave reflection.

Why it Matters
A marker of arterial stiffness, elevated augmentation pressure is associated with cardiovascular risk factors as well as increased cardiovascular morbidity and mortality.

 
augmentation indexAugmentation Index

What it Is
An indirect measure of arterial stiffness that increases with age, augmentation index reflects the burden stiff arteries place on the heart.

Why it Matters
Chronic stress on the heart and the cardiovascular system can lead to heart failure and hypertrophy (enlarged heart).

Hover over each biomarker above to learn more

Vascular Biomarkers

Vascular Biomarkers

Central Blood Pressure
Central Systolic and Diastolic Blood Pressure is the pressure in the ascending aorta, just outside the left ventricle. It is the pressure that the target organs are exposed to, and due to arterial pressure amplification is lower than brachial cuff pressures.
Brachial Blood Pressure
Brachial Systolic and Diastolic Blood Pressure is the pressure of blood at the brachial artery in the upper arm.
Medical Heart Rate
A beat-to-beat heart rate measurement on par with standard ECG-based methods. A consistently high resting rate may indicate heart disease.
Augmentation Pressure
Augmentation Pressure is the added pressure from the backward reflected pressure wave and is a measure of the extra work the heart must generate to eject oxygenated blood to the body. It is also a reflection of arterial stiffness, a consequence of aging and disease.
Augmentation Index
Augmentation Index is a measure of the percentage of the blood pressure on the heart not related to blood pumping, but to artery stiffness. This is indicative of the extra load on the heart which is shown to be a risk factor for major cardiovascular diseases.
Central Pulse Pressure
Central Pulse Pressure is the amount of pressure on the heart during the cardiac cycle. This pressure differs significantly from the pressure measured by conventional cuff blood pressure devices. A high central pulse pressure is indicative of major organ risk.
Subendocardial Viability Ratio
Subendocardial Viability Ratio (SEVR) is a measure reflecting the cardiac ability to supply oxygen to the body during high demand and can provide early indications of heart disease.
Pulse Wave Velocity
Pulse wave velocity measures arterial stiffness. Increases in arterial stiffness are generally based on the loss of elasticity in the aorta artery walls over time and increases the strain on the heart from heightened pressures. Increased aortic stiffness using PWV is a validated predictor of cardiovascular events and all-cause mortality.
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Convenient…Consistent…Complete

The SphygmoCor XCEL performs simple patient assessments using a blood pressure cuff to measure both brachial and central blood pressures. Within 3 minutes, the patient’s vascular biomarker results and central aortic pressure waveform are generated.

Pulse Wave Analysis (PWA) is an Essential Diagnostic Tool

Central blood pressure and brachial blood pressure are captured. Confirm patient hypertension with both central and brachial blood pressure values. The Oscar™ 2 with SphygmoCor® Inside is complementary to the XCEL, providing a 24-hour assessment of a patient’s day and night central and brachial blood pressure.

The full PWA suite of digital vascular biomarkers are used across multiple therapeutic areas, including but not limited to cardiovascular, oncology, nephrology, neuroscience, sports medicine, women’s health, metabolism, and immunology.

Download the PWA Guide

SphygmoCor XCEL PWA Software

The SphygmoCor XCEL PWA software provides clinicians and researchers with a patient’s real-time central aortic pressure waveform. Like a fingerprint, the waveform and suite of digital vascular biomarkers are unique to each patient. The PWA Software includes a personalized patient visit report that is compliant with HIPAA and GDPR regional requirements. Full biomarker data exporting and reporting support are available.

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