Maximize Your Success in Decentralized Trials with SphygmoCor^® Technology

ATCOR Chief Medical Officer Steven Kesten, MD discusses how to maximize success in decentralized clinical trials. For products targeting cardiovascular disease, incorporation of central aortic blood pressure (BP) measurement and monitoring can improve key decisions during development (go/no go, endpoints, population characteristics, benefit-risk profile, dosing, etc.) and enhance the likelihood of both regulatory and commercial success. The presentation reviews noninvasive central blood pressure measurement and the rationale for use in drug and medical device development programs.

As presented live at the DIA 2022 Global Annual Meeting in Chicago, Illinois

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Central Blood Pressure Can Effectively Predict Cardiovascular Risk!

Cardiologist Dr. Hunter Champion uses SphygmoCor^® XCEL to target medications and optimize hypertension care

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“ We need simple individualized guidelines based on central pressure. ”
—Cardiology Today

“ Precise measurement of cBP improves patient management decisions in hypertension. ”
—Lancet Commission on Hypertension

“ I use SphygmoCor in my preventive cardiology practice—it’s an integral component of my cardiovascular risk assessment. ”
—Lee Marcus MD, MS, FACC

What's new in Central Blood Pressure?

Managing Hypertension With Central Blood Pressure Insights

3d rendered illustration of the male heart

SphygmoCor^® technology helps clinicians better understand the drivers of hypertension—including central blood pressure and arterial stiffness. Assessment of central pressure waveforms enables individualized interventions, targeted medications, and lifestyle modifications.

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What is Central Blood Pressure And Why Is It So Important?

Hypertension leads to cardiovascular disease - the #1 killer in the developed world. See how ATCOR noninvasive central blood pressure measures blood pressure at target organs like the heart and kidneys.

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How Central Blood Pressure Impacts Health Economics

Diagnosing and treating patients using central blood pressure analysis may result in approximately $56B in annual savings and reduce the number of patients on prescription hypertension drugs by 16%.

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Central Blood Pressure’s Role
In Improving Cognitive Health

Early intervention through better diagnostics may prevent cerebrovascular disease, reduce cognitive decline, and improve brain health.

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Central Blood Pressure And Gestational Hypertension

Combining central blood pressure with brachial measurements improves risk assessment for women with hypertensive disorders of pregnancy.

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Using Central Aortic Pressure For Chronic Kidney Disease

Chronic kidney disease (CKD) is common and effects approximately 15% of adults in the USA (37 million people).

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The only cure for dementia is prevention.

Central blood pressure (cBP) and arterial stiffness may be early indicators of Alzheimer’s and other causes of dementia.^1,2

ATCOR noninvasive central blood pressure and pulse wave analysis enable clinicians to identify high-risk patients and target therapies to delay or prevent dementia.

1. Matsumoto et al,2020
2. Cui et al, 2018